Publications
Bridging AI Advancements with Risk Assessment Needs: A Journey Towards Effective Use and Regulatory Acceptance
Kolesnyk S. , De Paula Souza J., Bearth A., Aicher L., Wilks M.F., Mosig A., Fritsche E.
Toxicology, 1 Jun 2026
Hormonal changes in professional printers exposed to phthalates suggesting potential disturbances of the hypothalamic–pituitary–gonadal axis
Tiberiu M. Nita , Sonja A. Wrobel , David Vernez , Holger M. Koch , Pascal Wild , Fanny Zufferey, Serge Rudaz , Ludwig Stenz , Alex Odermatt , Nancy B. Hopf
Environmental Research, 15 Feb 2026
Bisphenol TMC exhibits greater estrogenic activity than Bisphenol A and three other structural analogues exemplified by higher estrogen receptor α-mediated gene expression and breast cancer cell proliferation
Joos, F. L., van Diest, R. E., Smieško, M., Jäger, M.-C., Kley, M., Odermatt, A., Bouitbir, J.
Elsevier ScienceDirect, 11 Feb 2026
New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption – a PARC project
Ardenkjær-Skinnerup, J., Baert, Y., Bajard, L., Blum, J., Brion, F., Coppola, L., Fini, J.-B., Fritsche, E., Holbech, H., Hurem, S., Jacobs, M. N., Johansson, H. K. L., Knapen, D., Lyche, J. L., Mai, P. N. T., Neuhaus, W., Nikolov, N. G. N., Nurani, A., Papageorgiou, K., Poulsen, R., Ramhøj, L., Řehůřková, E., Rosenmai, A. K., Rüegg, J., Sovadinová, I., Tait, S., Van de Pette, M., Vanhaecke, T., Vergauwen, L., Wedebye, E. B., Xu, E. G., Svingen, T.
Frontiers, 11 Feb 2026
Advancing the implementation of artificial intelligence in regulatory frameworks for chemical safety assessment by defining robust readiness criteria
Souza, J. de P., Blum, J., Maran, U., Sild, S., Dawson, L., Čavoški, A., Holden, L., Lee, R., Karnel, V., Meusburger, L., Fraize-Frontier, S., Walsh, A., Rivière, G., Raitano, G., Roncaglioni, A., Di Consiglio, E., Tcheremenskaia, O., Bossa, C., Wendt-Rasch, L., Puzyn, T., Fritsche, E.
Frontiers, 11 Feb 2026
Regulation of chemicals demands assessment of risks rather than identification of hazards only
Marx-Stoelting P, Ritz V, Herzler M, Kneuer C, Aiello-Holden K, Brescia S, Escher SE, Feustel S, Fritsche E, Gebel J, Kenny EF, Landsiedel R, Sanders P, Schwarz M, Streitz M, Testai E, van Ravenzwaay B, Waetjen W, Wend K, Wilks M, Luch A, Tralau T, Hensel A.
Archives of Toxicology, 7 Feb 2026
New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption – a PARC project
Ardenkjær-Skinnerup J, Baert Y, Bajard L, Blum J, Brion F, Coppola L, Fini JB, Fritsche E, Holbech H, Hurem S, Jacobs MN, Johansson HKL, Knapen D, Koch K, Lyche JL, Mai PNT, Neuhaus W, Nikolov NG, Nurani A, Papageorgiou K, Poulsen R, Ramhøj L, Řehůřková E, Rosenmai AK, Rüegg J, Sovadinová I, Tait S, Van de Pette M, Vanhaecke T, Vergauwen L, Wedebye EB, Xu EG, Svingen T.
Frontiers in Toxicology, 3 Feb 2026
Urinary concentrations of di-butyl phthalate isomers and reproductive hormonal parameters in adult men: A systematic review with dose-response meta-analysis
Tiberiu M. Nita, David Vernez, Pascal Wild, Nelly Pitteloud, Nancy B. Hopf
Environmental Toxicology and Pharmacology, 1 Jan 2026
Tattoo ink induces inflammation in the draining lymph node and alters the immune response to vaccination
Arianna Capucetti, Juliana Falivene, Chiara Pizzichetti, Irene Latino, Luca Mazzucchelli, Vivien Schacht, Urs Hauri , Andrea Raimond, Tommaso Virgilio , Alain Pulfer, Simone Mosole, Llorenç Grau- Roma, Wolfgang Bäumlr, Martin Palus, Louis Renner, Daniel Ruzek, Gabrielle Goldman Levy , Milena Foerster, Kamil Chahine, and Santiago F. Gonzalez
PNAS, 25 Nov 2025
Neurotoxicity of propylene glycol butyl ether: Multiomic evidence from human brainspheres
David Lopez-Rodriguez, David Pamies, Julien Boccard, Isabel Meister, Mathieu Galmiche, Tatjana Sajic, Estelle Maret, Noéline Héritier, Massimo Frangiamone, Aurélien Thomas, Nancy B. Hopf, Serge Rudaz, Marie-Gabrielle Zurich
Environment International, 22 Oct 2025