Publications

Bridging AI Advancements with Risk Assessment Needs: A Journey Towards Effective Use and Regulatory Acceptance

Kolesnyk S. , De Paula Souza J., Bearth A., Aicher L., Wilks M.F., Mosig A., Fritsche E.

Toxicology,  1 Jui 2026


Hormonal changes in professional printers exposed to phthalates suggesting potential disturbances of the hypothalamic–pituitary–gonadal axis

Tiberiu M. Nita , Sonja A. Wrobel , David Vernez , Holger M. Koch , Pascal Wild , Fanny Zufferey, Serge Rudaz , Ludwig Stenz , Alex Odermatt , Nancy B. Hopf

Environmental Research,  15 Fév 2026


Advancing the implementation of artificial intelligence in regulatory frameworks for chemical safety assessment by defining robust readiness criteria

Souza, J. de P., Blum, J., Maran, U., Sild, S., Dawson, L., Čavoški, A., Holden, L., Lee, R., Karnel, V., Meusburger, L., Fraize-Frontier, S., Walsh, A., Rivière, G., Raitano, G., Roncaglioni, A., Di Consiglio, E., Tcheremenskaia, O., Bossa, C., Wendt-Rasch, L., Puzyn, T., Fritsche, E.

Front Artif Intell.,  11 Fév 2026


New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption – a PARC project

Ardenkjær-Skinnerup, J., Baert, Y., Bajard, L., Blum, J., Brion, F., Coppola, L., Fini, J.-B., Fritsche, E., Holbech, H., Hurem, S., Jacobs, M. N., Johansson, H. K. L., Knapen, D., Lyche, J. L., Mai, P. N. T., Neuhaus, W., Nikolov, N. G. N., Nurani, A., Papageorgiou, K., Poulsen, R., Ramhøj, L., Řehůřková, E., Rosenmai, A. K., Rüegg, J., Sovadinová, I., Tait, S., Van de Pette, M., Vanhaecke, T., Vergauwen, L., Wedebye, E. B., Xu, E. G., Svingen, T.

Frontiers,  11 Fév 2026


Bisphenol TMC exhibits greater estrogenic activity than Bisphenol A and three other structural analogues exemplified by higher estrogen receptor α-mediated gene expression and breast cancer cell proliferation

Joos, F. L., van Diest, R. E., Smieško, M., Jäger, M.-C., Kley, M., Odermatt, A., Bouitbir, J.

Elsevier ScienceDirect,  11 Fév 2026


Regulation of chemicals demands assessment of risks rather than identification of hazards only

Marx-Stoelting P, Ritz V, Herzler M, Kneuer C, Aiello-Holden K, Brescia S, Escher SE, Feustel S, Fritsche E, Gebel J, Kenny EF, Landsiedel R, Sanders P, Schwarz M, Streitz M, Testai E, van Ravenzwaay B, Waetjen W, Wend K, Wilks M, Luch A, Tralau T, Hensel A.

Archives of Toxicology,  7 Fév 2026


Regulation of chemicals demands assessment of risks rather than identification of hazards only

Marx-Stoelting P, Ritz V, Herzler M, Kneuer C, Aiello-Holden K, Brescia S, Escher SE, Feustel S, Fritsche E, Gebel J, Kenny EF, Landsiedel R, Sanders P, Schwarz M, Streitz M, Testai E, van Ravenzwaay B, Waetjen W, Wend K, Wilks M, Luch A, Tralau T, Hensel A.

Archives of Toxicology,  7 Fév 2026


New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption – a PARC project

Ardenkjær-Skinnerup J, Baert Y, Bajard L, Blum J, Brion F, Coppola L, Fini JB, Fritsche E, Holbech H, Hurem S, Jacobs MN, Johansson HKL, Knapen D, Koch K, Lyche JL, Mai PNT, Neuhaus W, Nikolov NG, Nurani A, Papageorgiou K, Poulsen R, Ramhøj L, Řehůřková E, Rosenmai AK, Rüegg J, Sovadinová I, Tait S, Van de Pette M, Vanhaecke T, Vergauwen L, Wedebye EB, Xu EG, Svingen T.

Frontiers in Toxicology,  3 Fév 2026


Urinary concentrations of di-butyl phthalate isomers and reproductive hormonal parameters in adult men: A systematic review with dose-response meta-analysis

Tiberiu M. Nita, David Vernez, Pascal Wild, Nelly Pitteloud, Nancy B. Hopf

Environmental Toxicology and Pharmacology,  1 Jan 2026


Developmental neurotoxicity evaluation of di(2-ethylhexyl) phthalate (DEHP) and three alternative plasticizers in human neurospheres

Kühne BA, Klose J, Seeger B, Illa M, Muñoz-Torrero D, Koch K, Fritsche E, Barenys M

Environment International Elsevier,  1 Jan 2026