Publications by group

Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases

Rohrer SR
Vuorinen A
Herdlinger S
Kaserer T
Leugger S
International Journal of Molecular Sciences

Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects

Dolder PC
Strajhar P
Vizeli P
Hammann F
Frontiers in Pharmacology

Virtual screening applications in short-chain dehydrogenase/reductase research

The Journal of Steroid Biochemistry and Molecular Biology

Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids

Tonoli D
Jeanneret F
Imhof RM
Malagnino V
Patt M

Evaluation of tetrabromobisphenol A effects on human glucocorticoid and androgen receptors: a comparison of results from human- with yeast-based in vitro assays


An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposure

Spaggiari D
Toxicology and Applied Pharmacology

Exploring Omics data from designed experiments using analysis of variance multiblock Orthogonal Partial Least Squares

Analytica Chimica Acta

Disruption of steroidogenesis: Cell models for mechanistic investigations and as screening tools

The Journal of Steroid Biochemistry and Molecular Biology

Prediction of retention time in reversed-phase liquid chromatography as a tool for steroid identification

Randazzo GM
Tonoli D
Hambye S
Guillarme D
Jeanneret F
Nurisso A
Goracci L
Analytica Chimica Acta

Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects

Schmid Y
Liakoni E
Rentsch KM
Journal of Neuroendocrinology

Separation of substrates and closely related glucuronide metabolites using various chromatographic modes

Romand S
Guillarme D
Journal of Chromatography. A.

Longitudinal monitoring of endogenous steroids in human serum by UHPLC-MS/MS as a tool to detect testosterone abuse in sports

Ponzetto F
Mehl F
Baume N
Saugy M
Nicoli R
Analytical and Bioanalytical Chemistry

Evaluation of steroidomics by liquid chromatography hyphenated to mass spectrometry as a powerful analytical strategy for measuring human steroid perturbations

Journal of Chromatography

Evaluation and identification of dioxin exposure biomarkers in human urine by high-resolution metabolomics, multivariate analysis and in vitro synthesis

Toxicology Letters

Pharmacophore Models and Pharmacophore-Based Virtual Screening: Concepts and Applications Exemplified on Hydroxysteroid Dehydrogenases

Kaserer T
Akram M

Umweltchemikalien unter der Lupe - Wie Chemikalien den molekularen Wirkmechanismus beeinflussen

GIT Labor-Fachzeitschrift 9/2015

Steroidomic Footprinting Based on Ultra-High Performance Liquid Chromatography Coupled with Qualitative and Quantitative High-Resolution Mass Spectrometry for the Evaluation of Endocrine Disrupting Chemicals in H295R Cells

Chemical Research in Toxicology

Pistacia lentiscus Oleoresin: Virtual Screening and Identification of Masticadienonic and Isomasticadienonic Acids as Inhibitors of 11β-Hydroxysteroid Dehydrogenase 1

Seibert J
Papageorgiou VP
Rollinger JM
Assimopoulou AN
Planta Medica

Acute Effects of 3,4-Methylenedioxymethamphetamine and Methylphenidate on Circulating Steroid Levels in Healthy Subjects

Seibert J
Hysek CM
Penno CA
Schmid Y

Untargeted profiling of urinary steroid metabolites after testosterone ingestion: opening new perspectives for antidoping testing

Boccard J
Badoud F
Jan N
Nicoli R
Schweizer C
Pralong F
Veuthey JL
Baume N
Saugy M

A cocktail approach for assessing the in vitro activity of human cytochrome P450s: an overview of current methodologies

Spaggiari D
Geiser L
Journal of Pharmaceutical and Biomedical Analysis

Human urinary biomarkers of dioxin exposure: Analysis by metabolomics and biologically driven data dimensionality reduction

Badoud F
Pelclova D
Vlckova S
Rutledge DN
Hochstrasser D
Saurat JH
Toxicology Letters

Phenotyping of CYP450 in human liver microsomes using the cocktail approach

Spaggiari D
Geiser L
Analytical and Bioanalytical Chemistry

Ligand-based pharmacophore modeling and virtual screening for the discovery of novel 17β-hydroxysteroid dehydrogenase 2 inhibitors

Engeli R
Meyer A
Bachmann F
Griesser UJ
Journal of Medicinal Chemistry

Population normalization with ammonium in wastewater-based epidemiology: application to illicit drug monitoring

Been F
Rossi L
Ort C
Delémont O
Esseiva P
Environmental Science & Technology

Harnessing the complexity of metabolomic data with chemometrics

Boccard J
Journal of Chemometrics

Pharmacophore model refinement for 11β-hydroxysteroid dehydrogenase inhibitors: Search for modulators of intracellular glucocorticoid concentrations

Nashev LG
Rollinger JM
Molecular Informatics

Mass Spectrometry Metabolomic Data Handling for Biomarker Discovery

Proteomic and Metabolomic Approaches for Biomarker Discovery

In silico methods in the discovery of endocrine disrupting chemicals

The Journal of Steroid Biochemistry and Molecular Biology

Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1

Meyer A
Zielinska AE
Lavery GG
Drug Metabolism and Disposition: the Biological Fate of Chemicals