Publications 2017

PDMS-b-PMOXA polymersomes for hepatocyte targeting and assessment of toxicity

Kiene K
Schenk SH
Porta F
Ernst A
Witzigmann D
Grossen P
European Journal of Pharmaceutics and Biopharmaceutics
31/10/2017

Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines [Epub ahead of print]

Mingard C
Paech F
Journal of Applied Toxicology
26/10/2017

Unravelling the effects of multiple experimental factors in metabolomics, analysis of human neural cells with hydrophilic interaction liquid chromatography hyphenated to high resolution mass spectrometry [Epub ahead of print]

Journal of Chromatography. A.
25/10/2017

Comparing the Advanced REACH Tool's (ART) Estimates With Switzerland's Occupational Exposure Data

Gasic B
Schinkel J
Annals of Work Exposures and Health
01/10/2017

Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases

Rohrer SR
Vuorinen A
Herdlinger S
Kaserer T
Leugger S
International Journal of Molecular Sciences
19/09/2017

Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects

Dolder PC
Strajhar P
Vizeli P
Hammann F
Frontiers in Pharmacology
07/09/2017

Selective stimulation of the JAK/STAT signaling pathway by silica nanoparticles in human endothelial cells

Siegrist S
Kettiger H
Fasler-Kan E
Toxicology In Vitro
31/08/2017

The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells

Grünig D
Felser A
Toxicology in Vitro
31/08/2017

Intoxication by gamma hydroxybutyrate and related analogues: Clinical characteristics and comparison between pure intoxication and that combined with other substances of abuse

Miró Ò
Galicia M
Dargan P
Dines AM
Giraudon I
Heyerdahl F
Hovda KE
Yates C
Wood DM
Euro-DEN Research Group
Toxicology Letters
05/08/2017

Virtual screening applications in short-chain dehydrogenase/reductase research

The Journal of Steroid Biochemistry and Molecular Biology
31/07/2017

Pro-fibrotic compounds induce stellate cell activation, ECM-remodelling and Nrf2 activation in a human 3D-multicellular model of liver fibrosis

Weston A
Messner S
Lampart F
PLoS One
30/06/2017

Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis

Frontiers in Pharmacology
14/06/2017

Potential mechanisms of development-dependent adverse effects of the herbicide paraquat in 3D rat brain cell cultures

Zoia D
Schilt C
Greggio C
Fournier M
Do KQ
Neurotoxicology
31/05/2017

IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes

Archives of Toxicology
31/05/2017

Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072 [Epub ahead of print]

Paech F
Messner S
Spickermann J
Wind M
Schmitt-Hoffmann AH
Witschi AT
Howell BA
Church RJ
Woodhead J
Engelhardt M
Maurer M
Archives of Toxicology
23/05/2017

Hepatocellular Toxicity of Imidazole and Triazole Antimycotic Agents

Haegler P
Joerin L
Toxicological Sciences
01/05/2017

Characterisation of extracellular vesicle-subsets derived from brain endothelial cells and analysis of their protein cargo modulation after TNF exposure

Journal of Extracellular Vesicles
19/04/2017

Systems Toxicology: Real World Applications and Opportunities

Hartung T
Jennings P
Mirams GR
Peitsch MC
Rostami-Hodjegan A
Shah I
Sturla SJ
Chemical Research in Toxicology
17/04/2017

Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids

Tonoli D
Jeanneret F
Imhof RM
Malagnino V
Patt M
Toxicology
15/04/2017

OECD/EFSA Workshop on Developmental Neurotoxicity (DNT): The Use of Non-Animal Test Methods for Regulatory Purposes

Fritsche E
Crofton KM
Hernandez AF
Hougaard Bennekou S
Bal-Price A
Reaves E
Terron A
Solecki R
Gourmelon A
ALTEX
31/03/2017

Development and characterization of a human embryonic stem cell-derived 3D neural tissue model for neurotoxicity testing

Eggermann E
Charvet I
Toni N
Greggio C
Toxicology In Vitro
28/02/2017

Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay

Colaianna M
Peterson H
Kern I
Julien S
Baquié M
Pallocca G
Bosgra S
Sachinidis A
Hengstler JG
Leist M
Archives of Toxicology
31/01/2017

Hepatic Effects of Pharmacological Doses of Hydroxy-Cobalamin[c-lactam] in Mice

Haegler P
Grünig D
Berger B
PLoS One
30/01/2017

Testicular Dysgenesis Syndrome and Long-Lasting Epigenetic Silencing of Mouse Sperm Genes Involved in the Reproductive System after Prenatal Exposure to DEHP

PLoS One
13/01/2017