Publications 2017

ART, Stoffenmanager, and TRA: A Systematic Comparison of Exposure Estimates Using the TREXMO Translation System

Gasic B
Annals of Work Exposures and Health
15/12/2017

Unravelling the effects of multiple experimental factors in metabolomics, analysis of human neural cells with hydrophilic interaction liquid chromatography hyphenated to high resolution mass spectrometry

Journal of Chromatography. A.
08/12/2017

An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition [Epub ahead of print]

Terron A
Bal-Price A
Paini A
Monnet-Tschudi F
Bennekou SH
EFSA WG EPI1 Members
Leist M
Schildknecht S
Archives of Toxicology
05/12/2017

Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072

Messner S
Spickermann J
Wind M
Schmitt-Hoffmann AH
Witschi AT
Howell BA
Church RJ
Woodhead J
Engelhardt M
Maurer M
Archives of Toxicology
30/11/2017

PDMS-b-PMOXA polymersomes for hepatocyte targeting and assessment of toxicity

Kiene K
Schenk SH
Porta F
Ernst A
Witzigmann D
Grossen P
European Journal of Pharmaceutics and Biopharmaceutics
31/10/2017

Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines [Epub ahead of print]

Journal of Applied Toxicology
26/10/2017

Comparing the Advanced REACH Tool's (ART) Estimates With Switzerland's Occupational Exposure Data

Gasic B
Schinkel J
Annals of Work Exposures and Health
01/10/2017

Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases

Rohrer SR
Vuorinen A
Herdlinger S
Kaserer T
Leugger S
International Journal of Molecular Sciences
19/09/2017

Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects

Dolder PC
Strajhar P
Vizeli P
Hammann F
Frontiers in Pharmacology
07/09/2017

Selective stimulation of the JAK/STAT signaling pathway by silica nanoparticles in human endothelial cells

Siegrist S
Kettiger H
Fasler-Kan E
Toxicology In Vitro
31/08/2017

The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells

Toxicology in Vitro
31/08/2017

Intoxication by gamma hydroxybutyrate and related analogues: Clinical characteristics and comparison between pure intoxication and that combined with other substances of abuse

Miró Ò
Galicia M
Dargan P
Dines AM
Giraudon I
Heyerdahl F
Hovda KE
Yates C
Wood DM
Euro-DEN Research Group
Toxicology Letters
05/08/2017

Virtual screening applications in short-chain dehydrogenase/reductase research

The Journal of Steroid Biochemistry and Molecular Biology
31/07/2017

Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones

Toxicology
15/07/2017

Pro-fibrotic compounds induce stellate cell activation, ECM-remodelling and Nrf2 activation in a human 3D-multicellular model of liver fibrosis

Weston A
Messner S
Lampart F
PLoS One
30/06/2017

Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis

Frontiers in Pharmacology
14/06/2017

Potential mechanisms of development-dependent adverse effects of the herbicide paraquat in 3D rat brain cell cultures

Zoia D
Schilt C
Greggio C
Fournier M
Do KQ
Neurotoxicology
31/05/2017

IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes

Archives of Toxicology
31/05/2017

Hepatocellular Toxicity of Imidazole and Triazole Antimycotic Agents

Haegler P
Joerin L
Toxicological Sciences
01/05/2017

Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin

Brecht K
Riebel V
Couttet P
Wolf A
Chibout SD
Pognan F
Uteng M
Toxicology in Vitro
30/04/2017

Characterisation of extracellular vesicle-subsets derived from brain endothelial cells and analysis of their protein cargo modulation after TNF exposure

Journal of Extracellular Vesicles
19/04/2017

Systems Toxicology: Real World Applications and Opportunities

Hartung T
Jennings P
Mirams GR
Peitsch MC
Rostami-Hodjegan A
Shah I
Sturla SJ
Chemical Research in Toxicology
17/04/2017

Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids

Tonoli D
Jeanneret F
Imhof RM
Malagnino V
Patt M
Toxicology
15/04/2017

OECD/EFSA Workshop on Developmental Neurotoxicity (DNT): The Use of Non-Animal Test Methods for Regulatory Purposes

Fritsche E
Crofton KM
Hernandez AF
Hougaard Bennekou S
Bal-Price A
Reaves E
Terron A
Solecki R
Gourmelon A
ALTEX
31/03/2017

Development and characterization of a human embryonic stem cell-derived 3D neural tissue model for neurotoxicity testing

Eggermann E
Charvet I
Toni N
Greggio C
Toxicology In Vitro
28/02/2017

Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay

Colaianna M
Peterson H
Kern I
Julien S
Baquié M
Pallocca G
Bosgra S
Sachinidis A
Hengstler JG
Leist M
Archives of Toxicology
31/01/2017

Hepatic Effects of Pharmacological Doses of Hydroxy-Cobalamin[c-lactam] in Mice

Haegler P
Grünig D
Berger B
PLoS One
30/01/2017

Testicular Dysgenesis Syndrome and Long-Lasting Epigenetic Silencing of Mouse Sperm Genes Involved in the Reproductive System after Prenatal Exposure to DEHP

PLoS One
13/01/2017