Marcel Leist, PhD, is Director of the Center for Alternatives to Animal Testing in Europe (CAAT-Europe) and full Professor at the University of Konstanz (D). He holds an MSc in Toxicology from the University of Surrey (UK) and a PhD in Biochemical Pharmacology. After an assignment as assistant/associate professor of Toxicology at the University of Konstanz (Konstanz, D) from 1995-2000, he worked in the pharmaceutical company H. Lundbeck A/S (Copenhagen, DK) as Head of Department. Since 2006, he has held the endowed Doerenkamp-Zbinden chair for in vitro toxicology and biomedicine at the University of Konstanz (D). The research concentrates on neurotoxicity, and on in vitro models of developmental neurotoxicity and neurodegeneration. Moreover, he is a specialist for the use of human stem cells in toxicology, for high content screens and for genome-wide analysis of toxicity pathways. His work, cited more than 12000 times, was published in over 160 peer-reviewed papers, and he is a member of several editorial and scientific advisory boards.