Professor Dr. Werner K. Lutz studied Chemistry at the Swiss Federal Institute of Technology (ETH Zürich) and received his doctoral degree in 1972. Postdoctoral activities comprised a one-year Course in Experimental Medicine at the University of Zürich and a Fellowship of the Swiss National Science Foundation at Rockefeller University in New York City. In 1975, he returned to Switzerland to join the new Institute of Toxicology of the ETH and the University of Zürich in Schwerzenbach near Zürich as a Research Group Leader for Chemical Carcinogenesis. He became Lecturer in Toxicology in 1980 and received the title of Professor in 1988. In 1994, he was appointed to the Chair of Toxicology at the Institute of Pharmacology and Toxicology of the University of Würzburg, Germany. He retired in spring 2009. His major interest is in mechanism-based cancer risk assessment, with emphasis on genotoxicity of chemical carcinogens, and investigations of dose-response relationships. The latter include both experimental and theoretical approaches, nonlinear and nonmonotonic shapes of dose-response curves, and consideration of factors that determine individual susceptibility.