Concensus on inflammation in AOPs

Arising from an expert meeting at the EU-JRC in September 2017, including SCAHT researcher Florianne Tschudi-Monnet, this paper provides a consensus on how to best represent inflammation in a way that is biologically appropriate yet is generalisable enough to facilitate AOP network connectivity; it thus represents a significant step forward in the evolution and application of the AOP framework. See publication.

MAS Toxicology (Geneva/Lausanne) - Registration until 15 June 2018

For graduates employed in a toxicological discipline who wish to obtain a recognized academic qualification in toxicology; fulfils the educational requirements of national and international professional bodies towards registration as a toxicologist. 

September 2018 - June 2020 (modules can be taken individually). Registration deadline 15 June 2018. Further information.

Swiss Diagnostic Start-Up Day - Swissbiolabs Award 2018

Business ideas can be presented at the Swiss Diagnostics Start-Up Day 2018 to an expert jury and investors. This event will take place on Thursday, 21 June 2018 at the University of Applied Sciences and Arts Northwestern Switzerland (FHNW) in Olten, Switzerland. Application is open until 30 April 2018. 

Every presented business idea will be rated by an expert jury. The best idea will be awarded with the "Swissbiolabs Award 2018". In addition, participants can profit from free office space, coaching programs, mentoring and networking. See further information.

New liver cancer biomarker

Congratulations to SCAHT research group leader Prof. Luigi Terracciano and other collaborators of Prof. Michael N Hall at the University of Basel on their recent Nature publication (Hindupur et al 2018) describing the discovery of protein LHPP as a key tumor suppressor in mouse and human in vitro liver cancer cells; in patients, low levels of LHPP were associated with increased tumour severity and reduced overall survival. LHPP could thus be used as a highly useful biomarker for diagnosis and prognosis of liver cancer. See publication.

10th Anniversary of the Ecotox Centre

The use of bioassays to assess water quality has many advantages and the acceptance of bioassays has increased in recent years - a trend to which the Ecotox Centre has contributed through its work. For this reason, the Ecotox Centre organises a symposium on the occasion of its 10th anniversary on the topic of "Environmental monitoring with bioassays". The focus is on the use and opportunities of bioassays for the regulatory monitoring of surface waters and sediments in Switzerland. The aim of the event is to provide experts from environmental agencies, private companies and academia with more in-depth practical information. For further information visit this website.

EUSAAT 2018, 23 - 26 September 2018, Linz (A) - Abstract submission deadline: 31 May 2018

17th Annual Congress of the European Society for Alternatives to Animal Testing (EUSAAT). See further information.

CEFIC-LRI Award 2018 - Improved alignment of the AOP concept in toxicology with the needs of risk assessment

The European Chemical Industry Council(Cefic), in conjunction with the Society of Environmental Toxicology and Chemistry (SETAC), the Association of European Toxicologists and European Societies of Toxicology (EUROTOX), and the International Society of Exposure Sciences (ISES), is offering a €100.000 award to support promising new research in the field of mammalian and environmental toxicology, with a specific focus on the improved alignment of the Adverse Outcome Pathway (AOP) concept in toxicology with the needs of risk assessment. See further information.

OECD launches QSAR Toolbox version 4.2

5 February 2018 - OECD launches QSAR Toolbox version 4.2. The Toolbox is a software application intended to the use of governments, chemical industry and other stakeholders in filling gaps in (eco)toxicity data needed for assessing the hazards of chemicals. For further information see this OECD website.

Bisphenol A: EU reduces limits for food contact materials

The EU Commission has published a new Regulation, to apply from 6 September 2018, that lowers the regulatory specific migration limit ('SML') for BPA in food contact materials from 0.6 to 0.05 mg/kg food and extends it to coating materials which are used to line food and drink cans. See also Q&A of the European Commission regarding Bisphenol A.

Draft guidance document for endocrine disruptors available for comments until 31 January 2018

The European Food Safety Authority (EFSA) and the European Chemicals Agency (ECHA) are inviting interested parties to comment on the draft guidance document for identifying endocrine disruptors under EU legislation for pesticides and biocides.

This draft guidance, which was requested by the European Commission, has been developed by the two agencies with the support of the Commission’s Joint Research Centre (JRC). In 2017 EFSA and ECHA conducted two targeted consultations on initial versions of the draft guidance with experts representing Member States and with stakeholders from industry and NGOs. SCAHT Director Martin Wilks contributed to this exercise on behalf of the European Association of Poison Centres and Clinical Toxicologists (EAPCCT). Following discussions with the European Commission, EFSA and ECHA are now inviting all interested parties to comment on the updated draft text by using the dedicated web form (links to EFSA and ECHA). The deadline for providing comments is 31 January 2018.