CAAT Researchers Create "Mini-Brains" in Lab to Study Neurological Diseases

Researchers at the Johns Hopkins Bloomberg School of Public Health have developed tiny “mini-brains” made up of many of the neurons and cells of the human brain - and even some of its functionality - which can be replicated on a large scale. The researchers say that the creation of these “mini-brains” could dramatically change how new drugs are tested for effectiveness and safety, taking the place of the hundreds of thousands of animals used for neurological scientific research in the United States. More information.

WBAL-TV Report (video): "Mini-brains" Could Reduce Need to Use Animals in Medical Testing.

Tox Info App now available for iPhone/iPad and Android

Tox Info Suisse (Tel. 145) provides medical information on acute poisoning. The Tox Info App is now available for iPhone/iPad and Android. For installation information click here.

PISC offers awards for AOP development

The PETA International Science Consortium Ltd. (PISC) is sponsoring a competition to encourage contributions to a collaborative resource for adverse outcome pathway (AOP) development. The AOP Wiki was created by the European Commission’s Joint Research Centre, EPA, and the Organisation for Economic Co-operation and Development to provide an interactive and virtual platform for AOP development and to promote international consensus on the developed AOPs. To encourage new contributors to add to existing entries in the AOP Wiki using available data, PISC is offering cash awards to the best contributions to the AOP Wiki by new users. The competition runs through March 15 and is open only to people who have made no contributions to the AOP Wiki before September 15, 2015. Prospective competitors must register with PISC. More information and registration instructions are available on the PISC website.

Season's Greetings


Dear colleagues and friends of the SCAHT,

The sixth year of our centre is almost complete. A year with many challenges and achievements including the first financial audit of the foundation accounts, a process audit by the State Secretariat for Education, Research and Innovation and, not least, the submission for our application for the next financing period to the Swiss Confederation. While these activities are necessary to demonstrate good governance of our centre and set us up for the future, it is our contribution to education, research and regulatory projects in toxicology and risk assessment which add value and support public health in Switzerland and abroad.

We wish you and your family a wonderful festive season with time for tranquility and reflection and a very happy and healthy New Year 2016!

                       Martin Wilks and the SCAHT team

EUROTOX 2017 - Extended deadline for submission of scientific proposals

There is still time to submit a scientific proposal for the EUROTOX 2017 Congress "Connecting for a safer future" that will be held in Bratislava, Slovakia, 10 - 13 September 2017. 

Submit your scientific proposals using this form making sure to include the organiser details, the recommended speakers, and a brief presentation of the proposal. Send your proposals via email to the EUROTOX Secretariat by 18 December 2015.

Last chance to register for course on "Modelling Approaches in Chemical Risk Assessment"

Module 6 of the CAS Regulatory Sciences program will take place from 30 November to 4 December 2015 at the University of Basel. Further details on content and registration.

Prof. Marcel Leist receives Animal Welfare Research Award 2015

We would like to congratulate our Science Advisory Board member Prof. Marcel Leist and his group on receiving the Animal Welfare Research Price 2015 from the German Federal Ministry of Food and Agriculture. This prize supports the development of methods to reduce and replace animal experiments. Further information (in German).

Photo source: Thomas Koehler/photothek/BMEL

Systems Toxicology 2016

Building on the highly successful 2013 Systems Toxicology conference in Ascona, the 2016 meeting explores current and likely future specific applications of systems toxicology approaches in chemical risk evaluation.

Reserve the date! Systems Toxicology 2016, 27 - 29 January. Program onlineRegistration now open.

SCAHT review on cadmium and uranium in mineral phosphate fertilizers

SCAHT has reviewed human and environmental risks from cadmium and uranium in mineral phosphate fertilizers for the Swiss Federal Office for Agriculture (Bundesamt für Landwirtschaft BLW/Office fédéral de l’agriculture OFAG). The results of these reviews can be found in the following reports:

  • Cadmium in mineral fertilisers – human and environmental risk update. FitzGerald R, Roth N. 13 March 2015.
  • Human and environmental impact of uranium derived from mineral phosphate fertilizers. Roth N, FitzGerald R. 19 June 2015.

​Link to reports.

Federal Council publishes report on strengthening 3R research in Switzerland

The Federal Council has published a report on the future of the 3R Research Foundation Switzerland and alternatives for animal experiments. The report points to several key activities for successful and sustainable 3R implementation: education and training, publication of 3R-relevant information, and strengthening 3R research. For the latter, the report asks the State Secretariat for Education, Research and Innovation and the Federal Food Safety and Veterinary Office to evaluate the possibility of creating a 3R Competence Centre modeled on the example of the SCAHT. 

For further information, please refer to the media information and the report: German version & French version