Publications

Using pluripotent stem cells and their progeny as an in vitro model to assess (developmental) neurotoxicity

Hoelting L, Leist M, Stoppini L

Methods and Principles in Medicinal Chemistry: "Predictive Toxicology - From Vision to Reality" (Eds. Pfannkuch F. and Suter-Dick L.), Vol 64. Wiley-VCH Publisher,  26 Sep 2014


Establishment of rodent and human in vitro systems for the investigation of testicular toxicity

Gastaldello A, Escoffier J, Kustermann S, Clemann N, Nef S, Stoppini L

Toxicology Letters,  10 Sep 2014


Hepatic toxicity of dronedarone in mice: Role of mitochondrial β-oxidation

Felser A, Stoller A, Morand R, Schnell D, Donzelli M, Terracciano L, Bouitbir J, Krähenbühl S

Toxicology,  2 Sep 2014


Phenotyping of CYP450 in human liver microsomes using the cocktail approach

Spaggiari D, Geiser L, Daali Y, Rudaz S

Analytical and Bioanalytical Chemistry,  31 Aug 2014


Seizures after single-agent overdose with pharmaceutical drugs: Analysis of cases reported to a poison center

Reichert C, Reichert P, Monnet-Tschudi F, Kupferschmidt H, Ceschi A, Rauber-Lüthy C

Clinical Toxicology,  31 Jul 2014


Ligand-based pharmacophore modeling and virtual screening for the discovery of novel 17β-hydroxysteroid dehydrogenase 2 inhibitors

Vuorinen A, Engeli R, Meyer A, Bachmann F, Griesser UJ, Schuster D, Odermatt A

Journal of Medicinal Chemistry,  24 Jul 2014


Population normalization with ammonium in wastewater-based epidemiology: application to illicit drug monitoring

Been F, Rossi L, Ort C, Rudaz S, Delémont O, Esseiva P

Environmental Science & Technology,  15 Jul 2014


Engineering of midbrain organoids containing long-lived dopaminergic neurons

Tieng V, Stoppini L, Villy S, Fathi M, Dubois-Dauphin M, Krause KH

Stem Cells and Development,  1 Jul 2014


The association of cytochrome P450 genetic polymorphisms with sulfolane formation and the efficacy of a busulfan-based conditioning regimen in pediatric patients undergoing hematopoietic stem cell transplantation

Uppugunduri CR, Rezgui MA, Diaz PH, Tyagi AK, Rousseau J, Daali Y, Duval M, Bittencourt H, Krajinovic M, Ansari M

The Pharmacogenomics Journal,  30 Jun 2014


T Cells Infiltrate the Liver and Kill Hepatocytes in HLA-B(∗)57:01-Associated Floxacillin-Induced Liver Injury

Wuillemin N, Terracciano L, Beltraminelli H, Schlapbach C, Fontana S, Krähenbühl S, Pichler WJ, Yerly D

The American Journal of Pathology,  30 Jun 2014