21 Feb 2019

7 New AOPs

The OECD Environment, Health and Safety Division requests review and endorsement of 7 Adverse Outcome Pathways (AOPs):

• AOP 6: PPARα antagonism leading to body-weight loss
• AOP 10: Blocking iGABA receptor ion channel leading to seizures
• AOP 21: AhR mediated mortality
• AOP 42: TPO Inhibition and Altered Neurodevelopment
• AOP 54: NIS inhibition and learning and memory impairment
• AOP 131: AhR activation-uroporphyria
• AOP 150: AhR activation to ELS mortality, via VEGF
  

Deadline for comments is 29 March 2019.
See further details