Publications

State of the science on assessing developmental neurotoxicity using new approach methods [online ahead of print]

Debad SJ, Aungst J, Carstens K, Ferrer M, Fitzpatrick S, Fritsche E, Geng Y, Hartung T, Hogberg HT, Li R, Mangas I, Marty S, Musser S, Perron M, Rattan S, Rüegg J, Sachana M, Schenke M, Shafer TJ, Smirnova L, Talpos J, Tanguay RL, Terron A, Bandele O

ALTEX,  9 Dec 2024


Potential antiandrogenic effects of parabens and benzophenone-type UV-filters by inhibition of 3α-hydroxysteroid dehydrogenases

Kley M, Stücheli S, Ruffiner P, Temml V, Boudon S, Schuster D, Odermatt A

Toxicology,  1 Dec 2024


In Vitro Hepatic Metabolism Input Parameters Support Toxicokinetic Simulations for the Formation of Methoxy Propionic Acid From β-Isomer Propylene Glycol Methyl Ether

Werner S, Hegg L, Hopf NB, Borgatta M, Suter-Dick L

Pharmacology Research & Perspectives,  1 Dec 2024


Transcriptomic characterization of 2D and 3D human induced pluripotent stem cell-based in vitro models as New Approach Methodologies for developmental neurotoxicity testing [online ahead of print]

Lislien M, Kuchovska E, Kapr J, Duale N, Andersen JM, Dirven H, Myhre O, Fritsche E, Koch K, Wojewodzic MW

Toxicology,  15 Nov 2024


International STakeholder NETwork (ISTNET) Workshop for creating a developmental and reproductive toxicity (DART) testing roadmap for regulatory purposes

Fritsche E, Aspiroz LS, Arand M, Faustman E, Müller I

ALTEX,  22 Oct 2024


Assessment of the potential risk of oteseconazole and two other tetrazole antifungals to inhibit adrenal steroidogenesis and peripheral metabolism of corticosteroids

Jäger MC, González-Ruiz V, Joos FL, Winter DV, Boccard J, Degenhardt T, Brand S, Rudaz S, Thompson GR, Odermatt A

Frontiers in Pharmacology,  8 Aug 2024


Hyphenation of microflow chromatography with electrospray ionization mass spectrometry for bioanalytical applications focusing on low molecular weight compounds: A tutorial review [online ahead of print]

Girel S, Meister I, Glauser G, Rudaz S

Mass Spectrometry Reviews,  1 Jul 2024


New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project

Tal T, Myhre O, Fritsche E, Rüegg J, Craenen K, Aiello-Holden K, Agrillo C, Babin PJ, Escher BI, Dirven H, Hellsten K, Dolva K, Hessel E, Heusinkveld HJ, Hadzhiev Y, Hurem A, Jagiello K, Judzinska B, Klüver N, Knoll-Gellida A, Kühne BA, Leist M, Lislien M, Lyche JL, Müller F, Colbourne JK, Neuhaus W, Pallocca G, Seeger B, Scharkin I, Scholz S, Spjuth O, Torres-Ruiz M, Bartmann K

Frontiers in Toxicology,  26 Apr 2024


Intuitive toxicology in the 21st century-Bridging the perspectives of the public and risk assessors in Europe [online ahead of print]

Bearth A, Roth N, Wilks MF, Siegrist M

Risk Analysis,  15 Mar 2024


Development of a generic sample preparation method using dispersive liquid-liquid microextraction for the monitoring of leachable compounds in hospital pharmacy-prepared prefilled drug products

Bello W, Pezzatti J, Rudaz S, Sadeghipour F

Analytical Methods,  14 Mar 2024