Publications
Novel Strategy to Assess the Neurotoxicity of Organic Solvents Such as Glycol Ethers: Protocol for Combining In Vitro and In Silico Methods With Human-Controlled Exposure Experiments
Hopf NB, Suter-Dick L, Huwyler J, Borgatta M, Hegg L, Pamies D, Paschoud H, Puligilla RD, Reale E, Werner S, Zurich MG
JMIR Research Protocols, 18 Jan 2024
Repeated Human Exposure to Semivolatile Organic Compounds by Inhalation: Novel Protocol for a Nonrandomized Study
Reale E, Hopf NB, Breider F, Grandjean D, Pirard C, Charlier C, Koch HM, Berthet A, Suarez G, Borgatta M
JMIR Research Protocols, 10 Oct 2023
Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone
Nunes C, Proença S, Ambrosini G, Pamies D, Thomas A, Kramer NI, Zurich MG
Frontiers in Pharmacology, 6 Sep 2023
Zebrafish Larvae as an in vivo Model for Antimicrobial Activity Tests against Intracellular Salmonella
Hauswirth P, Buck J, Puligilla R, Alter CL, Sieber S, Claudi B, Fanous J, Bumann D, Huwyler J
Frontiers in Bioscience, 25 May 2023
High efficiency preparation of monodisperse plasma membrane derived extracellular vesicles for therapeutic applications
Alter CL, Detampel P, Schefer RB, Lotter C, Hauswirth P, Puligilla RD, Weibel VJ, Schenk SH, Heusermann W, Schürz M, Meisner-Kober N, Palivan C, Einfalt T, Huwyler J
Communications Biology, 3 May 2023
Nephrotoxicity of iopamidol is associated with mitochondrial impairment in human cell and teleost models
Bolten JS , Mancuso RV, Roos NJ, Mayr A, Puligilla RD, Kraus L, Odermatt A, Fricker G, Huwyler J
Toxicology and Applied Pharmacology, 1 May 2023
Zebrafish (Danio rerio) larvae as a predictive model to study gentamicin-induced structural alterations of the kidney
Bolten JS, Tanner C, Rodgers G, Schulz G, Levano S, Weitkamp T, Waldner S, Puligilla RD, Bodmer D, Müller B, Huwyler J
PLoS One, 20 Apr 2023
Digoxin Induces Human Astrocyte Reaction In Vitro
Pamies D, Vujić T, Schvartz D, Boccard J, Repond C, Nunes C, Rudaz S, Sanchez JC, González-Ruiz V, Zurich MG
Molecular Neurobiology, 31 Jan 2023
Methotrexate-Induced Liver Injury Is Associated with Oxidative Stress, Impaired Mitochondrial Respiration, and Endoplasmic Reticulum Stress In Vitro
Schmidt S, Messner CJ, Gaiser C, Hämmerli C, Suter-Dick L
International Journal of Molecular Sciences, 1 Dec 2022
Quality criteria for in vitro human pluripotent stem cell-derived models of tissue-based cells
Pistollato F, Bal-Price, A, Coecke, S, Parvatam, S, Pamies, D, Czysz, K, Hao J, Kee K, Kee Keong Teo A, Niu S, Wilmes A, Smirnova L, Freund C, Mummery C, Stacey G
Reproductive Toxicology, 30 Sep 2022