Publications

State of the science on assessing developmental neurotoxicity using new approach methods [online ahead of print]

Debad SJ, Aungst J, Carstens K, Ferrer M, Fitzpatrick S, Fritsche E, Geng Y, Hartung T, Hogberg HT, Li R, Mangas I, Marty S, Musser S, Perron M, Rattan S, Rüegg J, Sachana M, Schenke M, Shafer TJ, Smirnova L, Talpos J, Tanguay RL, Terron A, Bandele O

ALTEX,  9 Dec 2024


Transcriptomic characterization of 2D and 3D human induced pluripotent stem cell-based in vitro models as New Approach Methodologies for developmental neurotoxicity testing [online ahead of print]

Lislien M, Kuchovska E, Kapr J, Duale N, Andersen JM, Dirven H, Myhre O, Fritsche E, Koch K, Wojewodzic MW

Toxicology,  15 Nov 2024


International STakeholder NETwork (ISTNET) Workshop for creating a developmental and reproductive toxicity (DART) testing roadmap for regulatory purposes

Fritsche E, Aspiroz LS, Arand M, Faustman E, Müller I

ALTEX,  22 Oct 2024


New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project

Tal T, Myhre O, Fritsche E, Rüegg J, Craenen K, Aiello-Holden K, Agrillo C, Babin PJ, Escher BI, Dirven H, Hellsten K, Dolva K, Hessel E, Heusinkveld HJ, Hadzhiev Y, Hurem A, Jagiello K, Judzinska B, Klüver N, Knoll-Gellida A, Kühne BA, Leist M, Lislien M, Lyche JL, Müller F, Colbourne JK, Neuhaus W, Pallocca G, Seeger B, Scharkin I, Scholz S, Spjuth O, Torres-Ruiz M, Bartmann K

Frontiers in Toxicology,  26 Apr 2024


Intuitive toxicology in the 21st century-Bridging the perspectives of the public and risk assessors in Europe [online ahead of print]

Bearth A, Roth N, Wilks MF, Siegrist M

Risk Analysis,  15 Mar 2024


The Clinical Toxicology Recommendations Collaborative: purpose, organization, and methodology [online ahead of print]

Wilks MF, Hoyte C, Cumpston KL, Hassanian-Moghaddam H, Tse ML, Ferrer-Dufol A, Thiermann H

Clinical Toxicology,  11 Mar 2024


Comprehensive mapping of the AOP-Wiki database: identifying biological and disease gaps

Jaylet T, Coustillet T, Smith NM, Viviani B, Lindeman B, Vergauwen L, Myhre O, Yarar N, Gostner JM, Monfort-Lanzas P, Jornod F, Holbech H, Coumoul X, Sarigiannis DA, Antczak P, Bal-Price A, Fritsche E, Kuchovska E, Stratidakis AK, Barouki R, Kim MJ, Taboureau O, Wojewodzic MW, Knapen D, Audouze K

Frontiers in Toxicology,  8 Mar 2024


Protocol for designing INVITES-IN, a tool for assessing the internal validity of in vitro studies

Svendsen C, Whaley P, Vist GE, Husøy, Beronius A, Di Consiglio E, Druwe I, Hartung T, Hatzi VI, Hoffmann S, Hooijmans CR, Machera K, Robinson JF, Roggen E, Rooney AA, Roth N, Spilioti E, Spyropoulou A, Tcheremenskaia O, Testai E, Vinken M, Mathisen GH

Evidence-Based Toxicology,  31 Aug 2023


Evaluating the food safety and risk assessment evidence-base of polyethylene terephthalate oligomers: A systematic evidence map

Schreier VN, Çörek E, Appenzeller-Herzog C, Brüschweiler BJ, Geueke B, Wilks MF, Schilter B, Muncke J, Simat TJ, Smieško M, Roth N, Odermatt A

Environment International,  30 Jun 2023


Use of the benchmark-dose (BMD) approach to derive occupational exposure limits (OELs) for genotoxic carcinogens: N-nitrosamines [online ahead of print]

Blum K, FitzGerald R, Wilks MF, Barle EL, & Hopf NB

Journal of Applied Toxicology,  9 Mar 2023