3 Oct 2019 - 4 Oct 2019
Altertox Academy Training: PBPK Modeling and quantitative in vitro-in vivo extrapolations
Physiologically based pharmacokinetic (PBPK) modelling plays a crucial role in next generation (non-animal) risk evaluations to inform the design of in vitro studies and to convert the data obtained with in vitro models into human dose−response or potency information. The goal of the course is to acquaint participants with setting up PBPK models based on non-animal input parameters and to subsequently use these models to extrapolate in vitro bioassay data to human dose-response or potency information.
Organizer
Altertox Academy
Location
The Netherlands
RIKILT Wageningen University and Research, Akkermaalsbos 2, 6708 Wageningen