Publications
Hepatic and Extra-Hepatic Metabolism of Propylene Glycol Ethers in the Context of Central Nervous System Toxicity [online ahead of print]
Werner S, Pamies D, Zurich MG, Suter-Dick L
Toxicology, 8 Fév 2025
New approach methodologies in human health risk assessment across European regulatory frameworks: Status quo, barriers and drivers for regulatory acceptance and use
Bearth A, Roth N, Jansen T, Holden L, Čavoški A, Di Consiglio E, Hauzenberger I, Lee R, Mombelli E, Tcheremenskaia O, Wendt-Rasch L, Wilks MF
Environment International, 1 Fév 2025
Editorial: Five grand challenges in toxicology
Fadeel B, Alexander J, Antunes SC, Dalhoff K, Fritsche E, Hogberg HT, Huaux F, Oredsson S, Pietroiusti A, Svingen T, Wilks MF
Frontiers in Toxicology, 21 Jan 2025
State of the science on assessing developmental neurotoxicity using new approach methods [online ahead of print]
Debad SJ, Aungst J, Carstens K, Ferrer M, Fitzpatrick S, Fritsche E, Geng Y, Hartung T, Hogberg HT, Li R, Mangas I, Marty S, Musser S, Perron M, Rattan S, Rüegg J, Sachana M, Schenke M, Shafer TJ, Smirnova L, Talpos J, Tanguay RL, Terron A, Bandele O
ALTEX, 9 Déc 2024
Potential antiandrogenic effects of parabens and benzophenone-type UV-filters by inhibition of 3α-hydroxysteroid dehydrogenases
Kley M, Stücheli S, Ruffiner P, Temml V, Boudon S, Schuster D, Odermatt A
Toxicology, 1 Déc 2024
In Vitro Hepatic Metabolism Input Parameters Support Toxicokinetic Simulations for the Formation of Methoxy Propionic Acid From β-Isomer Propylene Glycol Methyl Ether
Werner S, Hegg L, Hopf NB, Borgatta M, Suter-Dick L
Pharmacology Research & Perspectives, 1 Déc 2024
Transcriptomic characterization of 2D and 3D human induced pluripotent stem cell-based in vitro models as New Approach Methodologies for developmental neurotoxicity testing [online ahead of print]
Lislien M, Kuchovska E, Kapr J, Duale N, Andersen JM, Dirven H, Myhre O, Fritsche E, Koch K, Wojewodzic MW
Toxicology, 15 Nov 2024
Human skin absorption of three plasticizers: Diisononyl-1,2-cyclohexanedicarboxylate (DINCH), di(2-ethylhexyl) terephthalate (DEHTP), and di(2-ethylhexyl) adipate (DEHA)
Hopf NB, De Luca HP, Koch HM, Pälmke C, Berthet A, Reale E
Toxicology Letters, 31 Oct 2024
International STakeholder NETwork (ISTNET) Workshop for creating a developmental and reproductive toxicity (DART) testing roadmap for regulatory purposes
Fritsche E, Aspiroz LS, Arand M, Faustman E, Müller I
ALTEX, 22 Oct 2024
Assessment of the potential risk of oteseconazole and two other tetrazole antifungals to inhibit adrenal steroidogenesis and peripheral metabolism of corticosteroids
Jäger MC, González-Ruiz V, Joos FL, Winter DV, Boccard J, Degenhardt T, Brand S, Rudaz S, Thompson GR, Odermatt A
Frontiers in Pharmacology, 8 Aoû 2024