Publications

Transcriptional regulation of CYP2C19 and its role in altered enzyme activity

Uppugunduri CR, Daali Y, Desmeules J, Dayer P, Krajinovic M, Ansari M

Current drug metabolism,  1 Oct 2012


Hepatic fat loss in advanced nonalcoholic steatohepatitis: Are alterations in serum adiponectin the cause?

van der Poorten D, Samer CF, Ramezani-Moghadam M, Coulter S, Kacevska M, Schrijnders D, Wu LE, McLeod D, Bugianesi E, Komuta M, Roskams T, Liddle C, Hebbard L, George J

Hepatology : official journal of the American Association for the Study of Liver Diseases,  19 Sep 2012


Pharmacokinetic interaction between prasugrel and ritonavir in healthy volunteers.

Ancrenaz V, Déglon J, Samer C, Staub C, Dayer P, Daali Y, Desmeules J

Basic & clinical pharmacology & toxicology,  21 Aoû 2012


Analgesics in patients with hepatic impairment: pharmacology and clinical implications

Bosilkovska M, Walder B, Besson M, Daali Y, Desmeules J

Drugs,  20 Aoû 2012


Liver kidney microsomal type 1 antibodies reduce the CYP2D6 activity in patients with chronic hepatitis C virus infection

Girardin F, Daali Y, Gex-Fabry M, Rebsamen M, Roux-Lombard P, Cerny A, Bihl F, Binek J, Moradpour D, Negro F, Desmeules J

Journal of viral hepatitis,  1 Aoû 2012


The paraoxonase-1 pathway is not a major bioactivation pathway of clopidogrel in vitro.

Ancrenaz V, Desmeules J, James R, Fontana P, Reny JL, Dayer P, Daali Y

British Journal of Pharmacology © 2012,  1 Aoû 2012


Effect of short- and long-term treatment with valproate on carnitine homeostasis in humans.

Morand R, Todesco L, Donzelli M, Fischer-Barnicol D, Mullen PJ, Krähenbühl S

Therapeutic drug monitoring,  30 Jui 2012


Feasibility of the extended one-generation reproductive toxicity study (OECD 443)

Fegert I, Billington R, Botham P, Carney E, FitzGerald RE, Hanley T, Lewis R, Marty MS, Schneider S, Sheets LP, Stahl B, van Ravenzwaay B

Reproductive toxicology (Elmsford, N.Y.),  9 Jui 2012


Toxicity of clopidogrel and ticlopidine on human myeloid progenitor cells: importance of metabolites.

Maseneni S, Donzelli M, Taegtmeyer AB, Brecht K, Krähenbühl S

Toxicology,  2 Jui 2012


Suppression of the Nrf2-dependent antioxidant response by glucocorticoids and 11β-HSD1-mediated glucocorticoid activation in hepatic cells.

Kratschmar DV, Calabrese D, Walsh J, Lister A, Birk J, Appenzeller-Herzog C, Moulin P, Goldring CE, Odermatt A

PloS one,  19 Mai 2012