Regulatory Toxicology Publications

Insights into possibilities for grouping and read-across for nanomaterials in EU chemicals legislation [Epub ahead of print]

Mech A
Rasmussen K
Jantunen P
Alessandrelli M
Bernauer U
Bleeker EAJ
Bouillard J
Di Prospero Fanghella P
Draisci R
Dusinska M
Encheva G
Flament G
Haase A
Handzhiyski Y
Herzberg F
Jacobsen NR
Jeliazkov V
Jeliazkova N
Nymark P
Grafström R
Oomen AG
Polci ML
Riebeling C
Shivachev B
Stateva S
Tanasescu S
Tsekovska R
Wallin H
Zellmer S
Apostolova MD
Nanotoxicology
05/09/2018

A quantitative risk assessment for skin sensitizing plant protection products: Linking derived No-Effect levels (DNELs) with agricultural exposure models [Epub ahead of print]

Sanvido O
Schmid K
Bormann P
Regulatory Toxicology and Pharmacology
29/07/2018

Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity

Bal-Price A
Hogberg HT
Crofton KM
Daneshian M
Fritsche E
Heinonen T
Hougaard Bennekou S
Klima S
Piersma AH
Sachana M
Shafer TJ
Terron A
Monnet-Tschudi F
Viviani B
Waldmann T
Westerink RHS
Witters H
Zurich MG
Leist M
ALTEX
09/07/2018

Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways

Villeneuve DL
Landesmann B
Allavena P
Ashley N
Bal-Price A
Corsini E
Halappanavar S
Hussell T
Laskin D
Lawrence T
Nikolic-Paterson D
Pallardy M
Paini A
Pieters R
Roth R
Tschudi-Monnet F
Toxicological Sciences
01/06/2018

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes [Epub ahead of print]

Fritsche E
Grandjean P
Crofton KM
Aschner M
Goldberg A
Heinonen T
Hessel EVS
Hogberg HT
Bennekou SH
Lein PJ
Leist M
Mundy WR
Paparella M
Piersma AH
Sachana M
Schmuck G
Solecki R
Terron A
Monnet-Tschudi F
Witters H
Bal-Price A
Toxicology and Applied Pharmacology
12/02/2018

An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition

Terron A
Bal-Price A
Paini A
Monnet-Tschudi F
Bennekou SH
EFSA WG EPI1 Members
Leist M
Schildknecht S
Archives of Toxicology
31/01/2018

Contrast-induced nephropathy: Basic concepts, pathophysiological implications and prevention strategies

Mamoulakis C
Tsarouhas K
Fragkiadoulaki I
Heretis I
Spandidos DA
Tsitsimpikou C
Tsatsakis A
Pharmacology & Therapeutics
31/12/2017

High-dose immunosuppression to prevent death after paraquat self-poisoning - a randomised controlled trial [Epub ahead of print]

Gawarammana I
Buckley NA
Mohamed F
Naser K
Jeganathan K
Ariyananada PL
Wunnapuk K
Dobbins TA
Tomenson JA
Eddleston M
Dawson AH
Clinical Toxicology (Phila)
03/11/2017

OECD/EFSA Workshop on Developmental Neurotoxicity (DNT): The Use of Non-Animal Test Methods for Regulatory Purposes

Fritsche E
Crofton KM
Hernandez AF
Hougaard Bennekou S
Bal-Price A
Reaves E
Terron A
Solecki R
Gourmelon A
ALTEX
01/05/2017

Systems Toxicology: Real World Applications and Opportunities

Hartung T
Jennings P
Mirams GR
Peitsch MC
Rostami-Hodjegan A
Shah I
Sturla SJ
Chemical Research in Toxicology
17/04/2017

A critical review of frameworks used for evaluating reliability and relevance of (eco)toxicity data: Perspectives for an integrated eco-human decision-making framework

Ciffroy P
Environment International
31/10/2016

Perspectives for integrating human and environmental exposure assessments

Ciffroy P
Péry AR
The Science of the Total Environment
15/10/2016

The European Registered Toxicologist (ERT): current status and prospects for advancement

Blaauboer BJ
Schulte-Hermann R
Wallace HM
Galli CL
Haag-Grönlund M
Matović V
Teixeira JP
Zilliacus J
Basaran N
Bonefeld-Jørgensen EC
Bourrinet P
Brueller W
Claude N
Miranda JP
Gundert-Remy U
Håkansson H
Kovatsi L
Liesivuori J
Lindeman B
Lison D
Leconte I
Martínez-López E
Murias M
Michel C
Scheepers PT
Stanley L
Tsatsakis A
Toxicology Letters
30/09/2016

Problem formulation for risk assessment of combined exposures to chemicals and other stressors in humans

Solomon KR
Bachman A
Boobis A
Moretto A
Pastoor TP
Phillips R
Embry MR
Critical Reviews in Toxicology
11/08/2016

White paper on the promotion of an integrated risk assessment concept in European regulatory frameworks for chemicals

Faust M
Papadaki P
Marchis A
Calliera M
Ginebreda A
Andres S
Kühne R
Schüürmann G
HEROIC consortium
The Science of the Total Environment
15/07/2015

International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes

Bal-Price A
Crofton KM
Allen S
Arand M
Buetler T
Delrue N
Hartung T
Heinonen T
Hogberg H
Bennekou SH
Lichtensteiger W
Oggier D
Paparella M
Axelstad M
Piersma A
Rached E
Schilter B
Schmuck G
Tongiorgi E
Tiramani M
Monnet-Tschudi F
Ylikomi T
Fritsche E
Archives of Toxicology
28/02/2015

Neurodevelopmental and neurobehavioural effects of polybrominated and perfluorinated chemicals: A systematic review of the epidemiological literature using a quality assessment scheme

Toxicology Letters
15/10/2014

Bisphenol A - Why an adverse outcome pathway framework needs to be applied

Toxicology Letters
15/10/2014

Environmental contaminants and target organ toxicities - new insights into old problems

Tsatsakis AM
Toxicology Letters
15/10/2014

Systems Toxicology: From Basic Research to Risk Assessment

Sturla SJ
Boobis AR
Hoeng J
Kavlock RJ
Schirmer K
Whelan M
Peitsch MC.
Chemical Research in Toxicology
17/03/2014

Perspectives for integrating human and environmental risk assessment and synergies with socio-economic analysis

Péry AR
Schüürmann G
Ciffroy P
Faust M
Backhaus T
Mombelli E
Tebby C
Cronin MT
Tissot S
Andres S
Brignon JM
Frewer L
Georgiou S
Mattas K
Vergnaud JC
Peijnenburg W
Capri E
Marchis A
The Science of the Total Environment
01/07/2013

Linking pesticide exposure and dementia: What is the evidence?

Zaganas I
Kapetanaki S
Mastorodemos V
Kanavouras K
Colosio C
Tsatsakis AM
Toxicology
10/05/2013

The interplay between environmental and genetic factors in Parkinson's disease susceptibility: The evidence for pesticides

Dardiotis E
Xiromerisiou G
Hadjichristodoulou C
Tsatsakis AM
Hadjigeorgiou GM
Toxicology
10/05/2013

Feasibility of the extended one-generation reproductive toxicity study (OECD 443)

Fegert I
Billington R
Botham P
Carney E
Hanley T
Lewis R
Marty MS
Schneider S
Sheets LP
Stahl B
van Ravenzwaay B
Reproductive toxicology (Elmsford, N.Y.)
09/06/2012

The ethics of human volunteer studies involving experimental exposure to pesticides: unanswered dilemmas.

London L
Coggon D
Moretto A
Westerholm P
Colosio C
Environmental health : a global access science source
20/08/2010

The value of acute toxicity studies to support the clinical management of overdose and poisoning: a cross-discipline consensus.

Chapman K
Creton S
Kupferschmidt H
Bond GR
Robinson S
Regulatory toxicology and pharmacology : RTP
16/07/2010