Publications by group

Removal of batch effects using stratified subsampling of metabolomic data for in vitro endocrine disruptors screening [Epub ahead of print]

Tonoli D
Strajhar P
Jeanneret F
Talanta
08/11/2018

Currently available murine Leydig cell lines can be applied to study early steps of steroidogenesis but not testosterone synthesis

Engeli RT
Fürstenberger C
Heliyon
28/02/2018

Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software

Marsousi N
Desmeules JA
Daali Y
Biopharmaceutics & Drug Disposition
31/01/2018

Enhanced metabolite annotation via dynamic retention time prediction: Steroidogenesis alterations as a case study

Randazzo GM
Tonoli D
Strajhar P
Xenarios I
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
15/12/2017

Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases

Engeli RT
Rohrer SR
Vuorinen A
Herdlinger S
Kaserer T
Leugger S
International Journal of Molecular Sciences
19/09/2017

Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases

Romand S
Spaggiari D
Marsousi N
Samer C
Desmeules J
Daali Y
Journal of Pharmaceutical and Biomedical Analysis
10/09/2017

Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects

Dolder PC
Strajhar P
Vizeli P
Hammann F
Frontiers in Pharmacology
07/09/2017

Virtual screening applications in short-chain dehydrogenase/reductase research

The Journal of Steroid Biochemistry and Molecular Biology
31/07/2017

Development of a New Extraction Device Based on Parallel-Electromembrane Extraction

Drouin N
Mandscheff JF
Schappler J
Analytical Chemistry
20/06/2017

High-resolution mass spectrometry as an alternative detection method to tandem mass spectrometry for the analysis of endogenous steroids in serum

Ponzetto F
Baume N
Kuuranne T
Saugy M
Nicoli R
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
01/05/2017

Inhibition of 11β-hydroxysteroid dehydrogenase 2 by the fungicides itraconazole and posaconazole

Bächler M
Vuorinen A
Wagner S
Akram M
Griesser U
Temml V
Klusonova P
Yamaguchi H
Biochemical Pharmacology
15/04/2017

Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids

Strajhar P
Tonoli D
Jeanneret F
Imhof RM
Malagnino V
Patt M
Toxicology
15/04/2017

Metabolomic analysis of urine samples by UHPLC-QTOF-MS: Impact of normalization strategies

Tonoli D
Lescuyer P
Ponte B
de Seigneux S
Martin PY
Schappler J
Analytica Chimica Acta
22/02/2017

Indirect Quantitative Structure-Retention Relationship for Steroid Identification: A chemometric challenge at “Chimiométrie 2016”

Randazzo GM
Vigneau E
Courcoux P
Harrouet C
Lijour Y
Dardenne P
Chemometrics and Intelligent Laboratory Systems, Volume 160, Pages 52-58
15/01/2017

Evaluation of tetrabromobisphenol A effects on human glucocorticoid and androgen receptors: a comparison of results from human- with yeast-based in vitro assays

Toxicology
31/08/2016

An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposure

Spaggiari D
Daali Y
Toxicology and Applied Pharmacology
01/07/2016

Exploring Omics data from designed experiments using analysis of variance multiblock Orthogonal Partial Least Squares

Analytica Chimica Acta
12/05/2016

Disruption of steroidogenesis: Cell models for mechanistic investigations and as screening tools

Strajhar P
Engeli RT
The Journal of Steroid Biochemistry and Molecular Biology
30/04/2016

Prediction of retention time in reversed-phase liquid chromatography as a tool for steroid identification

Randazzo GM
Tonoli D
Hambye S
Guillarme D
Jeanneret F
Nurisso A
Goracci L
Analytica Chimica Acta
15/04/2016

Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects

Strajhar P
Schmid Y
Liakoni E
Dolder PC
Rentsch KM
Journal of Neuroendocrinology
31/03/2016

Separation of substrates and closely related glucuronide metabolites using various chromatographic modes

Romand S
Guillarme D
Journal of Chromatography. A.
26/02/2016

Longitudinal monitoring of endogenous steroids in human serum by UHPLC-MS/MS as a tool to detect testosterone abuse in sports

Ponzetto F
Mehl F
Baume N
Saugy M
Nicoli R
Analytical and Bioanalytical Chemistry
31/01/2016

Evaluation of steroidomics by liquid chromatography hyphenated to mass spectrometry as a powerful analytical strategy for measuring human steroid perturbations

Jeanneret F
Tonoli D
Saugy M
Journal of Chromatography
22/01/2016

Evaluation and identification of dioxin exposure biomarkers in human urine by high-resolution metabolomics, multivariate analysis and in vitro synthesis

Jeanneret F
Tonoli D
Saurat JH
Sorg O
Toxicology Letters
05/01/2016

Pharmacophore Models and Pharmacophore-Based Virtual Screening: Concepts and Applications Exemplified on Hydroxysteroid Dehydrogenases

Kaserer T
Akram M
Molecules
19/12/2015

Umweltchemikalien unter der Lupe - Wie Chemikalien den molekularen Wirkmechanismus beeinflussen

GIT Labor-Fachzeitschrift 9/2015
15/09/2015

Steroidomic Footprinting Based on Ultra-High Performance Liquid Chromatography Coupled with Qualitative and Quantitative High-Resolution Mass Spectrometry for the Evaluation of Endocrine Disrupting Chemicals in H295R Cells

Tonoli D
Fürstenberger C
Jeanneret F
Chemical Research in Toxicology
18/05/2015

Pistacia lentiscus Oleoresin: Virtual Screening and Identification of Masticadienonic and Isomasticadienonic Acids as Inhibitors of 11β-Hydroxysteroid Dehydrogenase 1

Vuorinen A
Seibert J
Papageorgiou VP
Rollinger JM
Assimopoulou AN
Planta Medica
30/04/2015

Acute Effects of 3,4-Methylenedioxymethamphetamine and Methylphenidate on Circulating Steroid Levels in Healthy Subjects

Seibert J
Hysek CM
Penno CA
Schmid Y
Neuroendocrinology
31/12/2014

Untargeted profiling of urinary steroid metabolites after testosterone ingestion: opening new perspectives for antidoping testing

Boccard J
Badoud F
Jan N
Nicoli R
Schweizer C
Pralong F
Veuthey JL
Baume N
Saugy M
31/12/2014

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