Publications by group

Model-based estimation of lowest observed effect concentration from replicate experiments to identify potential biomarkers of in vitro neurotoxicity [Epub ahead of print]

Calderazzo S
Tavel D
Kopp-Schneider A
Archives of Toxicology

Human Neural Organoids for Studying Brain Cancer and Neurodegenerative Diseases

Cosset E
Locatelli M
Marteyn A
Lescuyer P
Dall Antonia F
Preynat-Seauve O
Tieng V
Journal of Visualized Experiments

Protein pathway analysis to study development-dependent effects of acute and repeated trimethyltin (TMT) treatments in 3D rat brain cell cultures [Epub ahead of print]

Walter N
Antinori P
Jeanneret F
Tonoli D
Monnet-Tschudi F
Toxicology In Vitro

An Integrative Multi-Omics Workflow to Address Multifactorial Toxicology Experiments

Pezzatti J
Jeanneret F
Tonoli D
Monnet-Tschudi F

Profiling the proteomic inflammatory state of human astrocytes using DIA mass spectrometry

Journal of Neuroinflammation

Longitudinal investigation of the metabolome of 3D aggregating brain cell cultures at different maturation stages by 1H HR-MAS NMR

Diserens G
Vermathen M
Vermathen P
Analytical and Bioanalytical Chemistry

Unravelling the effects of multiple experimental factors in metabolomics, analysis of human neural cells with hydrophilic interaction liquid chromatography hyphenated to high resolution mass spectrometry

Journal of Chromatography. A.

Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases

Romand S
Spaggiari D
Marsousi N
Samer C
Desmeules J
Daali Y
Journal of Pharmaceutical and Biomedical Analysis

Development of a New Extraction Device Based on Parallel-Electromembrane Extraction

Drouin N
Mandscheff JF
Schappler J
Analytical Chemistry

Potential mechanisms of development-dependent adverse effects of the herbicide paraquat in 3D rat brain cell cultures

Broyer A
Zoia D
Schilt C
Greggio C
Fournier M
Monnet-Tschudi F

High-resolution mass spectrometry as an alternative detection method to tandem mass spectrometry for the analysis of endogenous steroids in serum

Ponzetto F
Baume N
Kuuranne T
Saugy M
Nicoli R
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences

Characterisation of extracellular vesicle-subsets derived from brain endothelial cells and analysis of their protein cargo modulation after TNF exposure

Journal of Extracellular Vesicles

Development and characterization of a human embryonic stem cell-derived 3D neural tissue model for neurotoxicity testing

Eggermann E
Charvet I
Toni N
Greggio C
Broyer A
Monnet-Tschudi F
Toxicology In Vitro

Metabolomic analysis of urine samples by UHPLC-QTOF-MS: Impact of normalization strategies

Gagnebin Y
Tonoli D
Lescuyer P
Ponte B
de Seigneux S
Martin PY
Schappler J
Analytica Chimica Acta

Tollip, an early regulator of the acute inflammatory response in the substantia nigra

Humbert-Claude M
Duc D
Dwir D
Thieren L
Begka C
Legueux F
Velin D
Maillard MH
Monnet-Tschudi F
Tenenbaum L
Journal of Neuroinflammation

Cell type-specific expression and localization of cytochrome P450 isoforms in tridimensional aggregating rat brain cell cultures

Vichi S
Gemma S
Stanzel S
Kopp-Schneider A
Monnet-Tschudi F
Testai E
Toxicology In Vitro

International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes

Bal-Price A
Crofton KM
Allen S
Arand M
Buetler T
Delrue N
Hartung T
Heinonen T
Hogberg H
Bennekou SH
Lichtensteiger W
Oggier D
Paparella M
Axelstad M
Piersma A
Rached E
Schilter B
Schmuck G
Tongiorgi E
Tiramani M
Monnet-Tschudi F
Ylikomi T
Fritsche E
Archives of Toxicology

Putative adverse outcome pathways relevant to neurotoxicity

Bal-Price A
Crofton KM
Sachana M
Shafer TJ
Behl M
Forsby A
Hargreaves A
Landesmann B
Lein PJ
Louisse J
Monnet-Tschudi F
Paini A
Rolaki A
Schrattenholz A
Suñol C
van Thriel C
Whelan M
Fritsche E
Critical Reviews in Toxicology

Immediate and delayed effects of subchronic Paraquat exposure during an early differentiation stage in 3D-rat brain cell cultures [Epub ahead of print]

Zoia D
Althaus J
Antinori P
Mermoud J
Pak HS
Monnet-Tschudi F
Toxicology Letters

Repeated exposure to Ochratoxin A generates a neuroinflammatory response, characterized by neurodegenerative M1 microglial phenotype

Antinori P
Rosset R
Aschner M
Glück F
Monnet-Tschudi F

Using pluripotent stem cells and their progeny as an in vitro model to assess (developmental) neurotoxicity

Hoelting L
Leist M
Methods and Principles in Medicinal Chemistry: "Predictive Toxicology - From Vision to Reality" (Eds. Pfannkuch F. and Suter-Dick L.), Vol 64. Wiley-VCH Publisher

Seizures after single-agent overdose with pharmaceutical drugs: Analysis of cases reported to a poison center

Reichert C
Reichert P
Monnet-Tschudi F
Kupferschmidt H
Ceschi A
Rauber-Lüthy C
Clinical Toxicology

Engineering of midbrain organoids containing long-lived dopaminergic neurons

Tieng V
Villy S
Fathi M
Dubois-Dauphin M
Krause KH
Stem Cells and Development

Gene expression profiles of similarly derived human embryonic stem cell lines correlate with their distinct propensity to exit stemness and their different differentiation behavior in culture

Sterthaus O
Feutz AC
Zhang H
Pletscher F
Bruder E
Miny P
Lezzi G
De Geyter M
Cellular Reprogramming

Embryonic stem cell-based screen for small molecules: cluster analysis reveals four response patterns in developing neural cells

Kern I
Xu R
Julien S
Suter DM
Preynat-Seauve O
Baquié M
Poncet A
Combescure C
Thriel CV
Krause KH
Current Medicinal Chemistry

Human embryonic stemcell-derived test systems for developmental neurotoxicity: a transcriptomics approach

Krug AK
Kolde R
Gaspar JA
Rempel E
Balmer NV
Meganathan K
Vojnits K
Baquié M
Waldmann T
Ensenat-Waser R
Jagtap S
Evans RM
Julien S
Peterson H
Zagoura D
Kadereit S
Gerhard D
Sotiriadou I
Heke M
Natarajan K
Henry M
Winkler J
Marchan R
Bosgra S
Westerhout J
Verwei M
Vilo J
Kortenkamp A
Hescheler J
Hothorn L
Bremer S
van Thriel C
Krause KH
Hengstler JG
Rahnenführer J
Leist M
Sachinidis A.
Archives of Toxicology