Recent Publications

Currently available murine Leydig cell lines can be applied to study early steps of steroidogenesis but not testosterone synthesis

Heliyon
28/02/2018

Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity [Epub ahead of print]

Bal-Price A
Hogberg HT
Crofton KM
Daneshian M
Fritsche E
Heinonen T
Hougaard Bennekou S
Klima S
Piersma AH
Sachana M
Shafer TJ
Terron A
Monnet-Tschudi F
Viviani B
Waldmann T
Westerink RHS
Witters H
Zurich MG
Leist M
ALTEX
23/02/2018

An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition

Terron A
Bal-Price A
Paini A
Monnet-Tschudi F
Bennekou SH
EFSA WG EPI1 Members
Leist M
Schildknecht S
Archives of Toxicology
31/01/2018

Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells [Epub ahead of print]

Toxicology
16/01/2018

Contrast-induced nephropathy: Basic concepts, pathophysiological implications and prevention strategies

Mamoulakis C
Tsarouhas K
Fragkiadoulaki I
Heretis I
Spandidos DA
Tsitsimpikou C
Tsatsakis A
Pharmacology & Therapeutics
31/12/2017

Enhanced metabolite annotation via dynamic retention time prediction: Steroidogenesis alterations as a case study

Tonoli D
Strajhar P
Xenarios I
Journal of Chromatography B Analytical Technologies in the Biomedical and Life Sciences
15/12/2017

ART, Stoffenmanager, and TRA: A Systematic Comparison of Exposure Estimates Using the TREXMO Translation System

Gasic B
Annals of Work Exposures and Health
15/12/2017

Unravelling the effects of multiple experimental factors in metabolomics, analysis of human neural cells with hydrophilic interaction liquid chromatography hyphenated to high resolution mass spectrometry

Journal of Chromatography. A.
08/12/2017

Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072

Messner S
Spickermann J
Wind M
Schmitt-Hoffmann AH
Witschi AT
Howell BA
Church RJ
Woodhead J
Engelhardt M
Maurer M
Archives of Toxicology
30/11/2017

High-dose immunosuppression to prevent death after paraquat self-poisoning - a randomised controlled trial [Epub ahead of print]

Gawarammana I
Buckley NA
Mohamed F
Naser K
Jeganathan K
Ariyananada PL
Wunnapuk K
Dobbins TA
Tomenson JA
Eddleston M
Dawson AH
Clinical Toxicology (Phila)
03/11/2017