Publications 2013

Mass Spectrometry Metabolomic Data Handling for Biomarker Discovery

Proteomic and Metabolomic Approaches for Biomarker Discovery

Embryonic stem cell-based screen for small molecules: cluster analysis reveals four response patterns in developing neural cells

Kern I
Xu R
Julien S
Suter DM
Preynat-Seauve O
Baquié M
Poncet A
Combescure C
Thriel CV
Krause KH
Current Medicinal Chemistry

Engineered nanomaterial uptake and tissue distribution: from cell to organism

Kettiger H
Schipanski A
Wick P
International Journal of Nanomedicine

Hepatocellular toxicity of clopidogrel: Mechanisms and risk factors

Zahno A
Maseneni S
Lindinger PW
Brecht K
Free Radical Biology & Medicine

Carbimazole-induced, ANCA-associated, crescentic glomerulonephritis: case report and literature review.

Mavrakanas TA
Bouatou Y
Samer C
de Seigneux S
Meyer P
Renal Failure

Allopurinol hypersensitivity is primarily mediated by dose-dependent oxypurinol-specific T cell response

Yun J
Mattsson J
Schnyder K
Fontana S
Largiadèr CR
Pichler WJ
Yerly D
Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology

Quantification of plasma carnitine and acylcarnitines by high-performance liquid chromatography-tandem mass spectrometry using online solid-phase extraction

Morand R
Donzelli M
Haschke M
Analytical and Bioanalytical Chemistry

Characterization of a rat multi-cell type 3D-liver microtissue system

Messner S
Moritz W
Journal of Tissue Science & Engineering

Sulfamethoxazole induces a switch mechanism in T cell receptors containing TCRVβ20-1, altering pHLA recognition

Watkins S
Pichler WJ
PLoS One

T cell receptor variable β20-1 harbors a nucleotide binding pocket in the CDR2β loop

Watkins S
Pichler WJ
Open Journal of Immunology

Activating interactions of sulfanilamides with T cell receptors

Watkins S
Pichler WJ
Open Journal of Immunology

HLA-B*57:011 abacavir-naive individuals have specific T cells but no patch test reactivity

Schnyder B
Adam J
Rauch A
Thurnheer MC
Pichler WJ
The Journal of Allergy and Clinical Immunology

In silico methods in the discovery of endocrine disrupting chemicals

The Journal of Steroid Biochemistry and Molecular Biology

Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1

Meyer A
Vuorinen A
Zielinska AE
Strajhar P
Lavery GG
Drug Metabolism and Disposition: the Biological Fate of Chemicals

With the benefit of hindsight: trials using retrospective controls versus randomized controlled trials in clinical toxicology

Dawson AH
Clinical Toxicology

Evidence of drug-drug interactions through uptake and efflux transport systems in rat hepatocytes: implications for cellular concentrations of competing drugs

Daali Y
Millet P
Dayer P
Pastor CM
Drug Metabolism and Disposition: the Biological Fate of Chemicals

Perspectives for integrating human and environmental risk assessment and synergies with socio-economic analysis

Péry AR
Schüürmann G
Ciffroy P
Faust M
Backhaus T
Mombelli E
Tebby C
Cronin MT
Tissot S
Andres S
Brignon JM
Frewer L
Georgiou S
Mattas K
Vergnaud JC
Peijnenburg W
Capri E
Marchis A
The Science of the Total Environment

Applications of CYP450 Testing in the Clinical Setting

Samer C
Lorenzini KI
Rollason V
Daali Y
Molecular Diagnosis & Therapy

Green fluorescent protein-based monitoring of endoplasmic reticulum redox poise

Birk J
Ramming T
Appenzeller-Herzog C
Frontiers in Genetics

Toxicity of thienopyridines on human neutrophil granulocytes and lymphocytes

Maseneni S
Donzelli M
Brecht K

Highly sensitive capillary electrophoresis-mass spectrometry for rapid screening and accurate quantitation of drugs of abuse in urine

Kohler I
Schappler J
Analytica Chimica Acta

HLA Haplotype Determines Hapten or p-i T Cell Reactivity to Flucloxacillin

Wuillemin N
Adam J
Fontana S
Pichler WJ
Yerly D
Journal of Immunology

Linking pesticide exposure and dementia: What is the evidence?

Zaganas I
Kapetanaki S
Mastorodemos V
Kanavouras K
Colosio C
Tsatsakis AM

The interplay between environmental and genetic factors in Parkinson's disease susceptibility: The evidence for pesticides

Dardiotis E
Xiromerisiou G
Hadjichristodoulou C
Tsatsakis AM
Hadjigeorgiou GM

Carbonyl reduction of triadimefon by human and rodent 11β-hydroxysteroid dehydrogenase 1

Meyer A
Vuorinen A
Zielinska AE
Da Cunha T
Strajhar P
Lavery GG
Biochemical Pharmacology

A cell-based, multiparametric sensor approach characterises drug-induced cytotoxicity in human liver HepG2 cells

Seeland S
Török M
Kettiger H
Treiber A
Hafner M
Toxicology in Vitro

Mechanisms of hepatocellular toxicity associated with dronedarone--a comparison to amiodarone

Felser A
Blum K
Lindinger PW
Toxicological Sciences

Pharmacokinetic interaction between prasugrel and ritonavir in healthy volunteers

Ancrenaz V
Déglon J
Samer C
Staub C
Dayer P
Daali Y
Basic & Clinical Pharmacology & Toxicology

EasyProt--an easy-to-use graphical platform for proteomics data analysis.

Gluck F
Hoogland C
Antinori P
Robin X
Nikitin F
Zufferey A
Pasquarello C
Fétaud V
Dayon L
Müller M
Lisacek F
Geiser L
Sanchez JC
Journal of Proteomics

Human embryonic stemcell-derived test systems for developmental neurotoxicity: a transcriptomics approach

Krug AK
Kolde R
Gaspar JA
Rempel E
Balmer NV
Meganathan K
Vojnits K
Baquié M
Waldmann T
Ensenat-Waser R
Jagtap S
Evans RM
Julien S
Peterson H
Zagoura D
Kadereit S
Gerhard D
Sotiriadou I
Heke M
Natarajan K
Henry M
Winkler J
Marchan R
Bosgra S
Westerhout J
Verwei M
Vilo J
Kortenkamp A
Hescheler J
Hothorn L
Bremer S
van Thriel C
Krause KH
Hengstler JG
Rahnenführer J
Leist M
Sachinidis A.
Archives of Toxicology