Publications 2014

A cocktail approach for assessing the in vitro activity of human cytochrome P450s: an overview of current methodologies

Spaggiari D
Geiser L
Daali Y
Journal of Pharmaceutical and Biomedical Analysis

Missbrauch von Lachgas: drei Fallberichte.

Liakoni E
Schweiz Med Forum

Untargeted profiling of urinary steroid metabolites after testosterone ingestion: opening new perspectives for antidoping testing

Boccard J
Badoud F
Jan N
Nicoli R
Schweizer C
Pralong F
Veuthey JL
Baume N
Saugy M

Acute Effects of 3,4-Methylenedioxymethamphetamine and Methylphenidate on Circulating Steroid Levels in Healthy Subjects

Seibert J
Hysek CM
Penno CA
Schmid Y

Epigenetic Transgenerational Inheritance of Reproductive Disease

Transgenerational Epigenetics. Edited by Trygve Tollefsbol. Elsevier.

Enhancement of drug specific lymphocyte proliferation using CD25hi-depleted CD3+ effector cells

Srinoulprasert Y
Pichler WJ
International Archives of Allergy and Immunology

Inhibition of metabotropic glutamate receptor 5 induces cellular stress through pertussis toxin-sensitive Gi-proteins in murine BV-2 microglia cells

Chantong B
Lister A
Journal of Neuroinflammation

Anthracycline- dependent cardiotoxicity and extracellular matrix remodeling

Nikitovic D
Juranek I
Tzardi M
Tsatsakis A
Tzanakakis GN

Evaluation of sparfloxacin distribution by mass spectrometry imaging in a phototoxicity model

Boudon SM
Morandi G
Prideaux B
Staab D
Junker U
Stoeckli M
Bauer D
Journal of the American Society for Mass Spectrometry

Real-time monitoring of exhaled drugs by mass spectrometry

Berchtold C
Bosilkovska M
Daali Y
Walder B
Zenobi R
Mass Spectrometry Reviews

Environmental contaminants and target organ toxicities - new insights into old problems

Tsatsakis AM
Toxicology Letters

Dibutyltin promotes oxidative stress and increases inflammatorymediators in BV-2 microglia cells

Chantong B
Lister A
Toxicology Letters

Bisphenol A - Why an adverse outcome pathway framework needs to be applied

Toxicology Letters

Neurodevelopmental and neurobehavioural effects of polybrominated and perfluorinated chemicals: A systematic review of the epidemiological literature using a quality assessment scheme

Toxicology Letters

Immediate and delayed effects of subchronic Paraquat exposure during an early differentiation stage in 3D-rat brain cell cultures [Epub ahead of print]

Zoia D
Althaus J
Antinori P
Mermoud J
Pak HS
Monnet-Tschudi F
Toxicology Letters

AhR signalling and dioxin toxicity

Sorg O
Toxicology Letters

Human urinary biomarkers of dioxin exposure: Analysis by metabolomics and biologically driven data dimensionality reduction

Jeanneret F
Badoud F
Sorg O
Tonoli D
Pelclova D
Vlckova S
Rutledge DN
Samer CF
Hochstrasser D
Saurat JH
Toxicology Letters

Hepatocellular toxicity of benzbromarone: Effects on mitochondrial function and structure

Felser A
Lindinger PW
Schnell D
Mies S
Jenö P

Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice

Tao J
Calvisi DF
Ranganathan S
Cigliano A
Zhou L
Singh S
Jiang L
Fan B
Armeanu-Ebinger S
Ribback S
Dombrowski F
Evert M
Chen X
Monga SP

Repeated exposure to Ochratoxin A generates a neuroinflammatory response, characterized by neurodegenerative M1 microglial phenotype

Antinori P
Rosset R
Aschner M
Glück F
Monnet-Tschudi F

Geneva cocktail for cytochrome P450 and P-glycoprotein activity assessment using dried blood spot

Bosilkovska M
Samer CF
Déglon J
Rebsamen M
Staub C
Dayer P
Walder B
Daali Y
Clinical Pharmacology and Therapeutics

Using pluripotent stem cells and their progeny as an in vitro model to assess (developmental) neurotoxicity

Hoelting L
Leist M
Methods and Principles in Medicinal Chemistry: "Predictive Toxicology - From Vision to Reality" (Eds. Pfannkuch F. and Suter-Dick L.), Vol 64. Wiley-VCH Publisher

Establishment of rodent and human in vitro systems for the investigation of testicular toxicity

Gastaldello A
Escoffier J
Kustermann S
Clemann N
Toxicology Letters

Hepatic toxicity of dronedarone in mice: Role of mitochondrial β-oxidation

Felser A
Stoller A
Morand R
Schnell D
Donzelli M

Phenotyping of CYP450 in human liver microsomes using the cocktail approach

Spaggiari D
Geiser L
Daali Y
Analytical and Bioanalytical Chemistry

Seizures after single-agent overdose with pharmaceutical drugs: Analysis of cases reported to a poison center

Reichert C
Reichert P
Monnet-Tschudi F
Kupferschmidt H
Ceschi A
Rauber-Lüthy C
Clinical Toxicology

Ligand-based pharmacophore modeling and virtual screening for the discovery of novel 17β-hydroxysteroid dehydrogenase 2 inhibitors

Vuorinen A
Engeli R
Meyer A
Bachmann F
Griesser UJ
Journal of Medicinal Chemistry

Population normalization with ammonium in wastewater-based epidemiology: application to illicit drug monitoring

Been F
Rossi L
Ort C
Delémont O
Esseiva P
Environmental Science & Technology

Engineering of midbrain organoids containing long-lived dopaminergic neurons

Tieng V
Villy S
Fathi M
Dubois-Dauphin M
Krause KH
Stem Cells and Development

The association of cytochrome P450 genetic polymorphisms with sulfolane formation and the efficacy of a busulfan-based conditioning regimen in pediatric patients undergoing hematopoietic stem cell transplantation

Uppugunduri CR
Rezgui MA
Diaz PH
Tyagi AK
Rousseau J
Daali Y
Duval M
Bittencourt H
Krajinovic M
Ansari M
The Pharmacogenomics Journal