Publications All Publications

Accuracy, discriminative properties and reliability of a human ESC-based in vitro toxicity assay to distinguish teratogens responsible for neural tube defects [Epub ahead of print]

Feutz AC
Archives of Toxicology
10/08/2019

Toxicity of metamizole on differentiating HL60 cells and human neutrophil granulocytes [Epub ahead of print]

Rudin D
Duthaler U
Toxicology
26/07/2019

Model-based estimation of lowest observed effect concentration from replicate experiments to identify potential biomarkers of in vitro neurotoxicity [Epub ahead of print]

Calderazzo S
Tavel D
Kopp-Schneider A
Archives of Toxicology
19/07/2019

11β-hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor gamma [Epub ahead of print]

Beck KR
Kanagaratnam S
Jetten AM
Yamaguchi H
Journal of Lipid Research
04/07/2019

Human Neural Organoids for Studying Brain Cancer and Neurodegenerative Diseases

Cosset E
Locatelli M
Marteyn A
Lescuyer P
Dall Antonia F
Preynat-Seauve O
Tieng V
Journal of Visualized Experiments
28/06/2019

Drug-induced endocrine blood pressure elevation [Epub ahead of print]

Beck KR
Thompson GR
Pharmacological Research
15/06/2019

Genetic resistance to DEHP-induced transgenerational endocrine disruption

PLoS One
10/06/2019

Protein pathway analysis to study development-dependent effects of acute and repeated trimethyltin (TMT) treatments in 3D rat brain cell cultures [Epub ahead of print]

Walter N
Antinori P
Jeanneret F
Tonoli D
Monnet-Tschudi F
Toxicology In Vitro
07/06/2019

Posaconazole-Induced Hypertension Due to Inhibition of 11β-Hydroxylase and 11β-Hydroxysteroid Dehydrogenase 2

Thompson GR
Beck KR
Journal of the Endocrine Society
06/06/2019

Semen quality of young men in Switzerland: a nationwide cross‐sectional population‐based study

Priskorn L
Galli F
Vargas J
Van den Bergh M
Fusconi A
Garlantezec R
Jensen TK
Multigner L
Skakkebæk NE
Germond M
Jørgensen N
NICER Working Group
Andrology
21/05/2019

DynaStI: A Dynamic Retention Time Database for Steroidomics

Randazzo GM
Lehmann F
Garcia A
Xenarios I
Liechti R
Bridge A
Metabolites
30/04/2019

Authors' response to the letter to the editor by Jowsey et al.

Sanvido O
Schmid K
Bormann P
Regulatory Toxicology and Pharmacology
29/04/2019

An Integrative Multi-Omics Workflow to Address Multifactorial Toxicology Experiments

Pezzatti J
Jeanneret F
Tonoli D
Monnet-Tschudi F
Metabolites
24/04/2019

In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice [Epub ahead of print]

Broyer A
Poirot O
Marbet P
Chantong B
Dos Santos T
Chrast R
Monnet-Tschudi F
Archives of Toxicology
16/04/2019

Removal of batch effects using stratified subsampling of metabolomic data for in vitro endocrine disruptors screening

Tonoli D
Strajhar P
Jeanneret F
Talanta
01/04/2019

Molecular Toxicological Mechanisms of Synthetic Cathinones on C2C12 Myoblasts

Zhou X
Luethi D
Sanvee GM
International Journal of Molecular Sciences
28/03/2019

PGC-1β modulates statin-associated myotoxicity in mice

Singh F
Zoll J
Duthaler U
Charles AL
Laverny G
McWilliams TG
Metzger D
Geny B
Archives of Toxicology
28/02/2019

Effects of lisdexamfetamine on plasma steroid concentrations compared with d-amphetamine in healthy subjects: A randomized, double-blind, placebo-controlled study

Strajhar P
Vizeli P
Dolder PC
Journal of Steroid Biochemistry and Molecular Biology
28/02/2019

Preclinical hazard evaluation strategy for nanomedicines

Siegrist S
Cörek E
Detampel P
Wick P
Nanotoxicology
28/02/2019

Mechanisms of insulin resistance by simvastatin in C2C12 myotubes and in mouse skeletal muscle [Epub ahead of print]

Biochemical Pharmacology
20/02/2019

Presentations to the emergency department with non-medical use of benzodiazepines and Z-drugs: profiling and relation to sales data

Lyphout C
Yates C
Margolin ZR
Dargan PI
Dines AM
Heyerdahl F
Hovda KE
Giraudon I
Bucher-Bartelson B
Green JL
Euro-DEN Research Group
Wood DM
European Journal of Clinical Pharmacology
31/01/2019

Non-immunological toxicological mechanisms of metamizole-associated neutropenia in [Epub ahead of print]

Rudin D
Lanzilotto A
Bachmann F
Housecroft CE
Constable EC
Drewe J
Haschke M
Biochemical Pharmacology
14/01/2019

Steroid profiles in both blood serum and seminal plasma are not correlated and do not reflect sperm quality: Study on the male reproductive health of fifty young Swiss men

Garcia A
Gagnebin Y
Tonoli D
Jeanneret F
Clinical Biochemistry
31/12/2018

Optimizing drug discovery by Investigative Toxicology: Current and future trends [Epub ahead of print]

Beilmann M
Boonen H
Czich A
Dear G
Hewitt P
Mow T
Newham P
Oinonen T
Pognan F
Roth A
Valentin JP
Van Goethem F
Weaver RJ
Birk B
Boyer S
Caloni F
Chen AE
Corvi R
Cronin MTD
Daneshian M
Ewart LC
Hamilton GA
Hartung T
Kangas JD
Kramer NI
Leist M
Marx U
Polak S
Rovida C
Testai E
Van der Water B
Vulto P
Steger-Hartmann T
ALTEX
20/12/2018

Profiling the proteomic inflammatory state of human astrocytes using DIA mass spectrometry

Journal of Neuroinflammation
30/11/2018

Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice

Paech F
Abegg VF
Duthaler U
Toxicology
01/11/2018

Longitudinal investigation of the metabolome of 3D aggregating brain cell cultures at different maturation stages by 1H HR-MAS NMR

Diserens G
Vermathen M
Vermathen P
Analytical and Bioanalytical Chemistry
31/10/2018

Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites

Marsousi N
Daali Y
Fontana P
Reny JL
Ancrenaz-Sirot V
Calmy A
Desmeules JA
Samer CF
Clinical Pharmacokinetics
31/10/2018

A quantitative risk assessment for skin sensitizing plant protection products: Linking derived No-Effect levels (DNELs) with agricultural exposure models

Sanvido O
Schmid K
Bormann P
Regulatory Toxicology and Pharmacology
31/10/2018

Insights into possibilities for grouping and read-across for nanomaterials in EU chemicals legislation [Epub ahead of print]

Mech A
Rasmussen K
Jantunen P
Alessandrelli M
Bernauer U
Bleeker EAJ
Bouillard J
Di Prospero Fanghella P
Draisci R
Dusinska M
Encheva G
Flament G
Haase A
Handzhiyski Y
Herzberg F
Jacobsen NR
Jeliazkov V
Jeliazkova N
Nymark P
Grafström R
Oomen AG
Polci ML
Riebeling C
Shivachev B
Stateva S
Tanasescu S
Tsekovska R
Wallin H
Zellmer S
Apostolova MD
Nanotoxicology
05/09/2018