Jean-Charles Sanchez has been working since 1989 in the field of proteomics. He obtained his Ph.D. in Biochemistry at the Buckingham University (UK) in the field of proteomics and diabetes. Since 1995, he has been the head of the Biomedical Proteomics Group at the Faculty of Medicine, Geneva University. As a co-inventor of the proteome concept, he has soon evaluated the great impact proteomics could have in biomarker discovery. Since then, its efforts have been concentrated to this goal and important results have been obtained in various types of diseases such as stroke, neurodegenerative diseases and diabetes. All these results permit to develop new diagnostic, therapeutic and predictive tools. Jean-Charles Sanchez is the author or co-author of more than 200 papers in refereed journals as well as 30 book chapters and 30 patents. He is a founder of the Swiss Proteomics Society (SPS) and the European Proteomics Association (EuPA). He is the Editor in Chief of Translational Proteomics.